A New Study for Sciatica

If you have pain that radiates from your lower back down into your leg, you may have sciatica, a painful condition that affects millions of Australians each year. The most common cause of sciatica is a bulging disc in the lower spine, and the pain can be quite severe.

If you’re struggling with sciatica pain, you may qualify for the SALIENT Clinical Study, now being offered at select centres in Australia. The study is for an investigational, non-opioid single injection designed to relieve sciatica pain. Participants in the SALIENT study will receive care from a specialist pain doctor, and do not require a referral.


Sciatica is the name given to pain caused by irritation of the sciatic nerve, a long nerve that begins in the lower spine and extends down the back of each leg. The most common cause of sciatica is a bulging disc in the spine, but there may be other causes.

Sciatica pain varies from person to person. The location of the pain can be anywhere along the path of the sciatic nerve - ranging from the lower back and buttock, down behind the thigh and into the calf. The pain can feel like a cramp or may be excruciating and can make sitting or standing very difficult. For others, it is a sharp or shooting pain, or a “pins and needles” feeling.

Right now, doctors at select centres in Australia are conducting the SALIENT Clinical Study. The study is evaluating SX600 – an investigational, non-opioid single injection designed to provide long-term relief of sciatica pain. SX600 is a sustained-release product, which is designed to deliver small doses of a corticosteroid to the inflamed nerve over a period of time.

Further details can be found in the SALIENT Patient Brochure and the SALIENT FAQ Sheet. If you would like to see if you qualify for the SALIENT study go to the SALIENT Clinical Study website here.


The Australian Pain Management Association Ltd. (APMA) is a health promotion charity providing advocacy, information and practical support for people living with chronic (persistent) pain and their families. APMA is the consumer health organisation for all Australians who live with pain. APMA is your voice.


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